[CAS: 97540-22-2] S-Adenosyl-L-methionine disulfate tosylate

Physical and Chemical Properties of S-Adenosyl-L-methionine disulfate tosylate for sale

Introduction

S-adenosylmethionine (SAMe) is an important naturally occurring bioactive substance in the human body, and a decrease in its level can cause a series of hazards, especially bile stasis. In clinical practice, patients with chronic liver disease often have intrahepatic cholestasis (IHC), which can further exacerbate liver damage and in severe cases, lead to cirrhosis, liver failure, and even death. Extracorporeal supplementation of SAMe is an important treatment for improving IHC.

S-adenosylmethionine p-toluenesulfonic acid sulfate is a (2:1) salt of S-adenosylmethionine p-toluenesulfonic acid and sulfuric acid. Due to the instability of S-adenosylmethionine p-toluenesulfonic acid sulfate in air and light, it is usually sold in the form of sulfate. S-adenosylmethionine p-toluenesulfonic acid sulfate is commonly used as a photographic developer, antioxidant, antibacterial agent, and corrosion inhibitor. It is also used as an intermediate in fur and hair dye, as well as a drug called dichloroethane.

Usage of S-Adenosyl-L-methionine disulfate tosylate:

Ademetionine Sulfate Tosylate is a mixed salt form of the diasteremoer hydrogen sulfate of adenosine methionine ion and toluenesulfonic acid salt . Ademetionine has anti-inflammatory activity and is used to treat chronic liver disease

In vivo studies

It has shown that continuous oral administration of ademetionine to rats for 7 days induces the activity of CYP450 subtype CYP1A2, which may inhibit the activity of CYP2D6, CYP3A4, CYP2C19, and CYP2C9.

Storage Condition

S-adenosyl-L-methionine Disulfate Tosylate  should be stored in a dry, clean, and dark environment. It is strictly prohibited to mix it with toxic substances to avoid contamination. Store in a cool and ventilated warehouse. Stay away from sources of fire, heat, and water.

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